What Is Hemodiafiltration (HDF)? Benefits & How It Works
Hemodiafiltration (HDF) is an advanced type of dialysis treatment.
It is a combination of two methods:
- Hemodialysis → removes small waste products like urea and creatinine.
- Hemofiltration → removes larger waste products that normal dialysis often misses.
This means HDF can clean the blood more completely than standard dialysis, removing both smaller and larger wastes from the blood.
How is HDF Different?
- Special filter and fluid exchange: HDF uses a high-flux filter (dialyzer) and infuses extra clean fluid during treatment.
- Removes a wider range of toxins: Clears both small waste products and larger molecules that regular dialysis often leaves behind.
- More effective purification: Helps patients feel more energetic, less fatigued and better overall after sessions.
- Lower risk of complications: There is a lower risk of complications like low blood pressure during a HDF session.
Benefits of HDF Dialysis
- Better toxin removal → Better Quality of Life:
HDF removes toxins more efficiently compared to regular hemodialysis. This improves the overall well-being and Quality of Life.
- More stable blood pressure:
HDF balances fluids more gently, which helps prevent sudden drops in blood pressure. This means fewer dizzy spells or weakness during treatment.
- Fewer long-term complications:
By removing larger toxins, HDF helps protect the heart, bones, and nerves over the long run. This may reduce complications that can happen after years of regular dialysis. These complications can affect the heart, bones, nerves, the brain and so on.
- Improved quality of life:
Patients often notice a better appetite, better sleep, and more stamina to handle everyday life.
- More comfortable sessions:
HDF treatments are usually easier to tolerate — patients report fewer cramps, less nausea, and a reduced “washed out” feeling when dialysis ends.
Where is HDF Dialysis Available?
HDF dialysis is now available across several major Indian cities, making this advanced dialysis modality more accessible:
NephroPlus offers HDF in Mumbai, Nagpur, Dehradun, Chandigarh/Mohali, Pune, Gwalior, Ranchi, Bangalore, Hyderabad, Jaipur, and Coimbatore.
We keep adding HDF in more and more locations. Please check back to see if a city you live in has been added to this list. Call our Customer Care number (1800-120-001-001) to find out more or simply WhatsApp Hi to +91 88860 33310.
FAQs
Is HDF better than normal dialysis?
Yes. HDF clears both small and large toxins, which makes it more effective than standard dialysis.
Is HDF available in my city?
Yes. HDF dialysis is available in Mumbai, Nagpur, Dehradun, Chandigarh/Mohali, Pune, Gwalior, Ranchi, Bangalore, Hyderabad, Jaipur, and Coimbatore.
Does HDF take more time than regular dialysis?
No, treatment time is usually the same as standard dialysis sessions.
Is HDF more expensive than regular HD?
Yes, HDF is more expensive than regular HD because a better dialyzer, a special bloodline and other special consumables need to be used for this.
Can I do a mix of HD and HDF? Say 1 HDF per week and 2 HD sessions per week?
Yes, you can! That way you can get the benefits of better clearance while not impacting your expense too much.



